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The health benefits of the Cinchona tree bark were first by South American indians who used it to cure the disease malaria. When the low temperature in the body caused shivers, the drug was used to cure those shivers by relaxing the muscles. The taste is highly on the bitter side; hence, it is used to make medicine by a sweet liquid. This miracle drug made it in the news after the Spaniards went to Peru and then used it in Rome to cure the malaria pandemic in the year 1631. The priests became the prime importers and exporters of this magic potion. In the 17th century, King Charles was by quinine and then this drug became famous in Britain as well.